Iran's Supreme Leader Ayatollah Ali Khamenei said the country's policy towards the US, Syria and other countries will not change, despite the nuclear deal signed earlier this week.
During a speech in Tehran, marking the Islamic festival of Eid-ul-Fitr, the ayatollah said Iran still had sharp differences with the US, especially over the Middle East, and pledged continue to back Syria, Iraq, the Palestinians and "oppressed people" in Yemen and Bahrain, he said.
"Whether the [nuclear] deal is approved or disapproved, we will never stop supporting our friends in the region and the people of Palestine, Yemen, Syria, Iraq, Bahrain and Lebanon," Ayatollah Khamenei said. "Even after this deal our policy towards the arrogant US will not change."
"The Americans say they stopped Iran from acquiring a nuclear weapon," he said.
"They know it's not true. We had a fatwa [religious ruling] declaring nuclear weapons to be religiously forbidden under Islamic law. It had nothing to do with the nuclear talks.
"We have repeatedly said we don't negotiate with the US on regional or international affairs; not even on bilateral issues.
"There are some exceptions like the nuclear programme that we negotiated with Americans to serve our interests... US policies in the region are diametrically opposed with Iran's policies."